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Toluca vs Santos Laguna Prediction & Betting Tips – Liga MX, 21 Sep 2026

Toluca on Fire: Back the Diablos Rojos to Win by Two or More

Mon, 21 Sept, 02:00

Tip lostFinal score: Toluca 2–3 Santos Laguna

The Estadio Nemesio Diez is a fortress right now, and Santos Laguna are walking in with a 1-3-1 record over their last five. Toluca have won all five recent outings, conceding just twice across the whole run, and they put five past Atlas at home just days ago. Santos have scored in only 2 of their last 5 games, arriving short-handed with Amione and Di Yorio sidelined. Toluca own 4 wins from 5 in head-to-head meetings, averaging over two goals per game in this fixture. The model puts Toluca's win probability at 88 per cent, and the AH -1.5 line at 1.70 with bet365 gives real value on a side that keeps blowing opponents away. Santos cannot score, Toluca cannot stop scoring. AH -1.5 Toluca at 1.70 is the play.

Toluca kept 4 clean sheets in their last 5 matches across all competitions.Recent form - last 5 matches

The numbers behind the tip

Form · last five

TolucaWWWWW
Santos LagunaWLDLL

Goals per game · last five

Toluca2.8 scored · 0.4 conceded
Santos Laguna0.8 scored · 1.2 conceded

Head-to-head · last five

15.01.26Liga MX3–1O2.5
17.07.25Liga MX2–4O2.5
07.04.25Liga MX2–1O2.5
23.09.24Liga MX2–0U2.5
22.02.24Liga MX1–0U2.5
Verdict
Toluca -1.5 goals (win by 2+) @ 1.70 · 4/5

Predictions are editorial opinions based on the data available at publication - never a guarantee. Odds move and availability varies by region. 18+, please gamble responsibly. BeGambleAware.org · Joueurs Info Service